曾雪梅
博士，助理研究员，硕士生导师，福建省高层次人才
福建师范大学生命科学学院，南方生物医学研究中心
教育经历：
2012.9-2016.6 华中科技大学，化学与化工学院，学士
2016.9-2018.6 华中科技大学，国家光电实验室，硕士
2018.9-2021.9 华中科技大学，生命科学学院，博士，导师：刘笔锋教授
研究方向：
主要从事生物友好纳米材料在肿瘤代谢调控的创新诊疗策略，重点关注其在糖代谢、谷氨酰胺代谢、胆固醇代谢的代谢干扰治疗及其机制探索。先后主持国家自然科学基金青年项目，福建省科学基金面上项目，福建师范大学院级“溪源江”创新项目等，在ACS Appi. Mater. Interfaces., Nano Res., Chem. Eng. J., Anal. Chem.等SCI一区杂志发表相关论文。
已发表论文和专利：
Jinpeng Deng, Huilan Zhuang, Sijie Shao, Xuemei Zeng*, Panpan Xue, Tingjie Bai, Xiaoman Wang, Shijie Shangguan, Yuanchun Chen, Shuangqian Yan*, Wei Huang*, Mitochondrial-Targeted Copper Delivery for Cuproptosis-Based Synergistic Cancer Therapy, Advanced Healthcare Materials, 2024, https://doi.org/10.1002/adhm.202304522
Huilan Zhuang, Panpan Xue, Sijie Shao, Xuemei Zeng*, Shuangqian Yan*, In situ generation of hybrid alginate hydrogels for enhance breast tumor ferrotherapy through multiplex magnifyin redox imbalances, International Journal of Biological Macromolecules, 2024, 258, 128952, https://doi.org/10.1016/j.ijbiomac.2023.128952
Yihang Ruan, Huilan Zhuang, Xuemei Zeng*, Lili Lin, Xuechun Wang, Panpan Xue, Shan Xu, Qi Chen*, Shuangqian Yan*, Wei Huang*, Engineered Microbial Nanohybrids for Tumor-Mediated NIR II Photothermal Enhanced Ferroptosis/Cuproptosis and Immunotherapy, Advanced Healthcare Materials, 2023, 2302537, https://doi.org/10.1002/adhm.202302537 Title Page
Xuemei Zeng#, Pengjie Li#, Shuangqian Yan, Bi-Feng Liu*, Reduction/pH-responsive disassemblable MOF-microbial nanohybrid for targeted tumor penetration and synergistic therapy, Chemical Engineering Journal, 452, 2023, 139517. https://doi.org/10.1016/j.cej.2022.139517
Xuemei Zeng, Yihang Ruan, Qi Chen,*, Shuangqian Yan*, Wei Huang*, Biocatalytic cascade in tumor microenvironment with a Fe2O3/Au hybrid nanozyme for synergistic treatment of triple negative breast cancer, Chemical Engineering Journal, 452, 2023, 138422. https://doi.org/10.1016/j.cej.2022.138422
Yuqian Fu, Tingjie Bai, Panpan Xue, Qi Chen, Weili Deng, Shuangqian Yan*, and Xuemei Zeng*, Glycolysis inhibition for synergistic phototherapy of triple-negative breast cancer, Jounal of Materials and Chemistry B, 2023, 11, 10717, https://doi.org/10.1039/D3TB02059B
Pengjie Li#, Xuemei Zeng#, Shunji Li, Xufu Xiang, Peng Chen, Yiwei Li*, Bi-Feng Liu*, Rapid Determination of Phase Diagrams for Biomolecular Liquid-Liquid Phase Separation with Microfluidics, Analyst Chemistry, 2022, 94, 687−694, https://doi.org/10.1021/acs.analchem.1c02700
Shuangqian Yan,* Xuemei Zeng, Yu Wang,* and Bi-Feng Liu*, Biomineralization of Bacteria by a Metal–Organic Framework for Therapeutic Delivery, Advanced Healthcare Materials, 2020, 2000046, https://onlinelibrary.wiley.com/doi/10.1002/adhm.202000046 Front Cover
Xuemei Zeng, Shuangqian Yan, Peng Chen, Wei Du, and Bi-Feng Liu*, Modulation of tumor microenvironment by metal-organicframework-derived nanoenzyme for enhancing nucleus-targeted photodynamic therapy, Nano Research, 2020, 13(6): 1527–1535, https://doi.org/10.1007/s12274-020-2746-4
Xuemei Zeng#, Shuangqian Yan#, Chao Di, Mengcheng Lei, Peng Chen, Wei Du, Yang Jin,* and Bi-Feng Liu*, “All-in-One” Silver Nanoprism Platform for Targeted Tumo Theranostics, ACS Appliled Materials Interfaces, 2020, 12, 11329−11340, https://dx.doi.org/10.1021/acsami.9b21166
Shuangqian Yan#, Xuemei Zeng#, Yong’an Tang, Bi-Feng Liu,* Yu Wang, and Xiaogang Liu* Activating Antitumor Immunity and Antimetastatic Effect Through Polydopamine-Encapsulated Core–Shell Upconversion Nanoparticles, Advanced Materials, 2019, 1905825, https://doi.org/10.1002/adma.201905825
已授权专利：
燕双仟，曾雪梅。一种双金属硫化物纳米探针的制备及应用。已授权 专利号：ZL 2021 1 1320777.2
刘笔锋，曾雪梅，杜伟。结构稳定的三棱柱纳米银复合探针及其制备方法与应用。 已授权 专利号：ZL 2019 1 0068197.5
刘笔锋，曾雪梅。一种多孔性四氧化三锰纳米探针的制备及应用。 已授权 专利号：ZL 2019 1 1067190.8
刘笔锋，曾雪梅。一种金属有机框架纳米材料、其制备与应用。 已授权 专利号：ZL 2019 1 1064937.4
招聘信息
课题组常年招生具有化学/材料/生物医学等背景的硕士研究生，同时热忱欢迎具有化学、材料、医学、生物器件等研究背景的博士后加盟！