2025年：

[1] Zhuang Huilan, Zhang Yongjian, Fu Yajuan, Ke Dangjin, Chen Qi, Shao Sijie, Xue Panpan, Chen Yuanchun, Zeng Xuemei, Yan Shuangqian. Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy [J]. Advanced Science, 2025, 12(41): e04603.

[2] Shen Yangkun, Zhang Hucheng, Xue Mengzhou, Zheng Chunfu, Chen Qi. HSV-1 as a gene delivery platform for cancer gene therapy [J]. Trends Pharmacol Sci, 2025.

[3] Wu Junjun, Zhao Zhennan, Wu Hongsheng, Lin Sihuang, Huang Lin, Chen Guanjie, Yang Yi, Wang Hong, Yan Huijie, Shi Yonghui. Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles [J]. Advanced Science, 2025, 12(40): e09208.

[4] Chen Tao-Tao, Lu Qiuhua, Zheng Si-Ru, Fu Jiaqi, Chen Jing, Kang Lina, Wu Juhong, Luo Jiwei, Tong Jiangyang, Li Siying. Structure and mechanism of an actin-dependent bacterial phosphoryl AMPylase [J]. Nat Chem Biol, 2025: 1-11.

[5] Guan Hongxin, Wu Huan, Gan Mengrou, Zhang Jing, Wang Jiajun, Liu Siyao, Chen Shuyue, Jiao Yindi, Li Fan, Huang Shiqing. Contact-dependent antagonism is mediated by a T7SSb toxin effector–immunity protein pair via ADP-ribosylation [J]. Science Bulletin, 2025.

[6] Zheng Weiwei, Li Hongyu, Liu Mengxi, Wei Yuhang, Liu Bo, Li Zekai, Xiong Chenyang, Huang Shiqing, Hu Chunyi, Ouyang Songying. Molecular insights and rational engineering of a compact CRISPR-Cas effector Cas12h1 with a broad-spectrum PAM [J]. Signal Transduction Targeted Therapy, 2025, 10(1): 66.

[7] Wang Mengying, Zhang Dandan, Tian Xiu, Tong Jiangyang, Yao Yizhou, Wang Mingshu, Zhu Dekang, Jia Renyong, Chen Shun, Zhao Xinxin. Structural Basis and Mechanism of a Unique Haemophore in the Haem‐Iron Acquisition by Riemerella anatipestifer (Adv. Sci. 13/2025) [J]. Advanced Science, 2025, 12(13): 2570091.

[8] Feng Zhihua, He Xinyan, Lin Minhua, Zhao Heng, Chen Yao, Chen Jianghua, Li Zhaolong, Shen Yangkun, Chen Jianxin, Yang Xiaoyu. Genome-wide CRISPR screen identifies ALG5, ALG6, NF2, and FUT8 as key host proteins involved in transmissible gastroenteritis virus infection [J]. Int J Biol Macromol, 2025: 148770.

[9] Du Hekang, Cui Dongya, Hu Shun, Zhou Xueyuan, Lin Xiaofang, Fu Xiaodan, Feng Sisi, Xu Shan, Jian Wentin, Guo Yuanli. The induction of type I interferonopathy in Trex1-P212fs mice is mediated by activation of the cGAS-STING pathway [J]. Int J Biol Macromol, 2025: 143414.

[10] Chiang Zu-Chian, Xu Shan, Zhao Xiangqian, Liu Min, Lin Jizhen, Chen Qi. Generation and characterization of 7DC-DM1: a non-cleavable CD47-targeting antibody-drug conjugates with antitumor effects [J]. Int J Biol Macromol, 2025, 310: 142844.

[11] Feng Zhihua, Fu Yajuan, Yang Sheng, Zhao Heng, Lin Minhua, Liu Chuancheng, Huang Weili, He Xinyan, Chen Yao, Chen Jianxin. Siglec-15 is a putative receptor for porcine epidemic diarrhea virus infection [J]. Cellular Molecular Life Sciences, 2025, 82(1): 1-22.

[12] Huang Zhijian, Zhao Xiangqian, Jiang Zirong, Qiu Xiaoting, Sun Xinhao, Wang Dawei, Zhang Hucheng, Chen Qi, Tan Ruirong, Shen Yangkun. IP6K2 mutations as a novel mechanism of resistance to oncolytic virus therapy [J]. J Transl Med, 2025, 23(1): 311.

[13] Huang Luqiang, Ye Chenqian, Lin Xinye, Wang Axue, Ke Chongrong, Li Daliang. Ultrasensitive and specific fluorescent probe towards sulfites to monitor its residue in the traditional herbs [J]. Talanta, 2025: 128760.

[14] Huang Luqiang, Lu Yuxin, Wang Axue, Lai Liqing, Huang Shuling, Ke Chongrong, Li Daliang. Complementary assay to determine residual sulfite of the preserved fruit with ratiometric probe [J]. Journal of Food Composition Analysis, 2025: 108034.

[15] Sang Kai, Lu Congfei, Zhang Yangfan, Chen Qi. Quasipaa spinosa-Derived Parvalbumin Attenuates Exercise-Induced Fatigue via Calcium Homeostasis and Oxidative Stress Modulation in Exhaustively Trained Mice [J]. Nutrients, 2025, 17(12): 2043.

[16] Zhang Xiaoxiong, Du Hekang, Qiu Tao, Fu Honggao, Dai Jiawei, Lian Qiying, Yan Fang, Guo Dong, Lin Jinpei, Xu Shan. Tanshinone IIA alleviates myocarditis in Trex1-D18N lupus-like mice by inhibiting the interaction between STING and SEC24C [J]. Int Immunopharmacol, 2025, 156: 114659.

[17] Wang Chenxi, Zhao Xiangqian, Wang Dawei, Wu Jinyun, Lin Jizhen, Huang Weiwei, Shen Yangkun, Chen Qi. Analysis of prognostic factors and nomogram construction for postoperative survival of triple-negative breast cancer [J]. Front Immunol, 2025, 16: 1561563.

[18] Zeng Xiaojun, Chen Weiqing, Yang Junhan, Zhang Qinshu, Deng Weili, Huang Zhengrong, Li Daliang. Comprehensive insights about accurate susceptibility detection towards hydrogen sulfide for food safety and disease diagnosis [J]. Spectrochimica Acta Part A: Molecular Biomolecular Spectroscopy, 2025: 127061.

[19] Lin Jinpei, Lin Shufang, Lin Zengyan, Huang Zhengrong, Li Daliang. Peroxynitrite as biomarker to evaluate the rehabilitation of cisplatin in the resistant cells with miR-125a-5p by using fluorescent assay [J]. Spectrochimica Acta Part A: Molecular Biomolecular Spectroscopy, 2025, 330: 125663.

[20] Yan Fang, Zhang Xiyu, Li Daliang, Zhu Nengbo, Bao Hongli. Recent applications of the Sonogashira reaction in the synthesis of drugs and their derivatives: A review [J]. Appl Organomet Chem, 2025, 39(1): e7932.

[21] Chen Yanfang, Zhou Huanmin, Yu Jiamin, Gao Jing, Xue Shengyu, Ding Hong, Lin Hua, Luo Cheng. A patent review of BRD4 inhibitors (2020–present) [J]. Expert Opin Ther Pat, 2025, 35(4): 371-86.

2024年：

[1] Dual-site molecular glues for enhancing protein-protein interactions of the CDK12-DDB1, Zemin Zhang#, Yuanqing Li#, Jie Yang#, Jiacheng Li#, Xiongqiang Lin#, Ting Liu#, Shiling Yang, Jin Lin, Shengyu Xue, Jiamin Yu, Cailing Tang, Ziteng Li, Liping Liu, Zhengzheng Ye, Yanan Deng, Zhihai Li, Kaixian Chen, Hong Ding*, Cheng Luo*, Hua Lin*, Nature Communications, 2024, 15, 6477

[2] J.Q. Su*,#,, Chen W, Zhou F, et al. Inhibitory mechanisms of decoy receptor3 in cecal ligation and puncture-induced sepsis[J]. mBio,2024: e00521-24. 

[3] J.Q. Su*,#, Tong Z, Feng Z, et al. Protective effects of DcR3-SUMO on lipopolysaccharide-induced inflammatory cells and septic mice[J]. International Journal of Biological Macromolecules, 2024,,275: 133703. 

[4] J.Q.Su*,#, JXiao*, S Chen, et al. Aloin ameliorates cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating gut microbiota. Food Science and Human Wellness,2024.  

[5] Native Amino Group Directed Meta-Selective C−H Arylation of Primary Amines Via Pd/Norbornene Catalysis, Shasha Zhang,# Gong Zhang,# Jie Wang,# Yueyao Feng,# Zemin Zhang,# Si Xie, Ziying Lin, Shiling Yang, Jin Lin,* and Hua Lin*, Organic Letters, 2024, 26, 12, 2495–2499  

[6] Panpan Xue, Huilan Zhuang, Tingjie Bai, Xuemei Zeng*, Jinpeng Deng, Sijie Shao, Shuangqian Yan*. Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc-. Journal of Nanobiotechnology, 2024, 22:228

[7] Shufang Lin#, Chenqian Ye#, Zengyan Lin, Luqiang Huang*, Daliang Li*, Recent Progress of Near-infrared Fluorescent Probes in the Determination of Reactive Oxygen Species for Disease Diagnosis, Talanta, 268 (2024), 125264. https://doi.org/10.1016/j.talanta.2023.125264  

[8] Yangkun Shen, Xiangqian Zhao, Lizhu Chen, Xin Wang, Dawei Wang, Hucheng Zhang, Zuda Zheng, Weiwei Huang, Chunfu Zheng, Yu Chen, Chuanben Chen, Qi Chen. A modified HSV-1 oncolytic virus reconciles antiviral and antitumor immunity via promoting IFNβ expression and inhibiting PKR. IJBM, 2024, 274（2），133297. doi: 10.1016/j.ijbiomac.2024.133297. Epub 2024 Jun 24.   

[9] Zhang Y, Zhao H, Deng W, Lai J, Sang K, Chen Q*. Zebularine potentiates anti-tumor immunity by inducing tumor immunogenicity and improving antigen processing through cGAS-STING pathway. Commun Biol. 2024 May 16;7(1):587. doi: 10.1038/s42003-024-06271-w. PMID: 38755254; PMCID: PMC11099016.

[10] Xiangkai Zhen # , Biao Zhou # , Zihe Liu # , Xurong Wang # , Heyu Zhao # , Shuxian Wu , Zekai Li , Jiamin Liang , Wanyue Zhang , Qingjian Zhu , Jun He , Xiaoli Xiong , Songying Ouyang .Mechanistic basis for the allosteric activation of NADase activity in the Sir2-HerA antiphage defense system. Nat Commun. 2024 Oct 27;15(1):9269.doi: 10.1038/s41467-024-53614-6.

[11] Shu X#, Wang R#*, Li Z#, Xue Q#, Wang J, Liu J, Cheng F, Liu C, Zhao H, Hu C, Li J*, Ouyang S*, Li M*. CRISPR-repressed toxin-antitoxin provides herd immunity against anti-CRISPR elements. Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01693-3. 

[12] Fu J#, Li S#, Guan H#, Li C#, Zhao YB#, Chen TT, Xian W, Zhang Z, Liu Y, Guan Q, Wang J, Lu Q, Kang L, Zheng SR, Li J, Cao S, Das C, Liu X*, Song L*, Ouyang S*, Luo ZQ*. Legionella maintains host cell ubiquitin homeostasis by effectors with unique catalytic mechanisms. Nat Commun. 2024 Jul 15;15(1):5953. doi: 10.1038/s41467-024-50311-2.

[13] Wu J*, Wang H, Gao P, Ouyang S*. Pyroptosis: Induction and Inhibition Strategies for Diseases Immunotherapy. Acta Pharmaceutica Sinica B. 2024. DOI: https://doi.org/10.1016/j.apsb.2024.06.026.  

[14] Zhang H#, Shi M#, Ma X#, Liu M#, Wang N, Lu Q, Li Z, Zhao Y, Zhao H, Chen H, Zhang H, Jiang T*, Ouyang S*, Huo Y*, Bi L*. Type-III-A structure of mycobacteria CRISPR-Csm complexes involving atypical crRNAs. Int J Biol Macromol. 2024 Mar;260(Pt 2):129331. doi: 10.1016/j.ijbiomac.2024.129331.

[15] Zhen X#, Xu X#, Ye L#, Xie S#, Huang Z, Yang S, Wang Y, Li J*, Long F*, Ouyang S*. Structural basis of antiphage immunity by the prokaryotic Argonaute-associated SPARSA system. Nat Commun. 2024 Jan 11;15(1):450. doi: 10.1038/s41467-023-44660-7.

2023年：

[1] Jingqian Su, Biyun Guan, Kunsen Chen, Zhihua Feng, Kai Guo, Xue Wang, Jianbin Xiao, Siyuan Chen, Wenzhi Chen, Wenzhi Chen, Long Chen, and Qi Chen. Fucoxanthin Attenuates Inflammation via Interferon Regulatory Factor 3 (IRF3) to Improve Sepsis. J. Agric. Food Chem. 2023, 71, 33, 12497–12510. https://doi.org/10.1021/acs.jafc.3c03247.

[2] Haifen Luo, Wen Ma, Qi Chen, Zhen Yang, Yunlu Dai. Radiotherapy-activated tumor immune microenvironment: Realizing radiotherapy-immunity combination therapy strategies. Nano Today. Volume 53, December 2023, 102042. https://doi.org/10.1016/j.nantod.2023.102042.

[3] Wu JJ#, Chen GJ#, Fan CY#, Shen F#, Yang Y, Pang W, Zhao ZN, Guan HX, Wu H, Lu Y, Fu YJ, Chen Q, Zheng YT*, Ouyang S*. An Adjustable Adjuvant STINGsome for Tailoring the Potent and Broad Immunity against SARS-CoV-2 and Monkeypox Virus via STING and Necroptosis. Adv Funct Mater. 2023. DOI: 10.1002/adfm.202306010. 

[4] Wan L#, Hu P#, Zhang L#, Wang ZX#, Fleming J, Ni B, Luo J, Guan CX, Bai L, Tan Y, Liu H, Li N, Xiao T, Bai H, Zhang Y, Zhang XE, Wan K*, Bi L*, Ouyang S*, Zhang H*. Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene. Commun Biol. 2023 Feb 7;6(1):156. 

[5] Yueyao Feng,# Jie Wang,# Jie Yang,# Fengyuan Chen,# Zemin Zhang, Chongrong Ke, Jin Lin,* Hua Lin*, Native Amino Group Directed Site-Selective ε–C(sp2)-H Iodination of Primary Amines, Organic Letters, 2023, 25, 9, 1348–1352. 

[6] Mingyu Wang#, Rongkun Lin#, Jiacheng Li#, Yuying Suo#, Jing Gao, Liping Liu, Liyuan Zhou, Yicheng Ni, Ziqun Yang, Jie Zheng, Jin Lin, Hu Zhou*, Cheng Luo*, Hua Lin*, Journal of Medicinal Chemistry,2023, 2023, 66, 7, 4932–4951.

[7] Changqing Ye, Rui Huang, Mong-Feng Chiou, Bo Wang, Daliang Li* and Hongli Bao*，Synthesis of a new fluorophore: wavelength-tunable bisbenzo[f]isoindolylidenes, Chem. Sci., 2023, 14, 13151.

[8] Luqiang Huang, Liqing Lai, Xinyue Zhang, Shufang Lin, Gang Jin, Daliang Li*，Development of a Practical NIR Fluorescent Ratiometric Assay for Detecting Residual Sulfite in the Wine, LWT, 189 (2023) 115503.

2022年：

[1] Wang D#, Zhu L#, Zhen X#, Yang D, Li C, Chen Y, Wang H, Qu Y, Liu X, Yin Y, Gu H, Xu L, Wan C, Wang Y, Ouyang S*, Shen X*. A secreted effector with a dual role as a toxin and as a transcriptional factor. Nat Commun. 2022 Dec 16;13(1):7779. doi: 10.1038/s41467-022-35522-9.

[2] Pang W#, Lu Y#, Zhao YB#, Shen F#, Fan CF , Wang Q, He WQ, He XY, Li ZK, Chen TT, Yang CX, Li YZ, Xiao SX, Zhao ZJ, Huang XS, Luo RH, Yang LM, Zhang  M, Dong XQ, Li MH, Feng XL, Zhou QC, Qu W, Jiang S*, Ouyang S*, Zheng YT*. A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein. Cell Research. 2022 Nov 10. DOI: 10.1038/s41422-022-00746-3.

[3] Li S#, Sun H#, Li J, Zhao Y, Wang R, Xu L, Duan C, Li J, Wang Z, Liu Q, Wang Y, Ouyang S*, Shen X*, Zhang L*. Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone. Nat Commun. 2022 Nov 5;13(1):6684. DOI: 10.1038/s41467-022-34607-9.

[4] Zhang B#, Lin J#, Perčulija V#, Li Y, Lu Q, Jing Chen J, Ouyang S*. Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system. Nucleic Acids Res. 2022 Nov 2;gkac987. DOI: 10.1093/nar/gkac987. 

[5] Zhao YB#, Liu MX#, Chen TT#, Ma X, Li ZK, Zheng Z, Zheng SR, Chen L, Li YZ, Tang LR, Chen Q, Wang P*, Ouyang S*. Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Science Advances. 2022 Sep 9;8(36):eabq5108.DOI: 10.1126/sciadv.abq5108.

[6] Zhen X#, Wu Y#, Ge J#, Fu J, Ye L, Lin N, Huang Z, Liu Z, Luo ZQ, Qiu J*, Ouyang S*. Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun. 2022 Jul 26;13(1):4333. DOI: 10.1038/s41467-022-32049-x.

[7] Zhang D, Liu Y, Zhu Y, Zhang Q, Guan H, Liu S, Chen S, Mei C, Chen C, Liao Z, Xi Y, Ouyang S, Feng XH, Liang T, Shen L, Xu P. A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis. Nat Cell Biol. 2022 May;24(5):766-782. DOI:10.1038/s41556-022-00894-z.

[8] Zheng X, Xiao H, Chen J, Zhu J, Fu Y, Ouyang S, Chen Y, Duo Chen, Su J, and Xue T. Metabolome and Whole-Transcriptome Analyses Reveal the Molecular Mechanisms Underlying Hypoglycemic Nutrient Metabolites Biosynthesis in Cyclocarya paliurus Leaves During Different Harvest Stages. Front Nutr. 2022 Feb 28;9: 851569. DOI: 10.3389/fnut.2022.851569.

[9] Xuemei Zeng, Yihang Ruan, Qi Chen*, Shuangqian Yan*, Wei Huang*. Biocatalytic cascade in tumor microenvironment with a Fe2O3/Au hybrid nanozyme for synergistic treatment of triple negative breast cancer. Chemical Engineering Journal 452 (2023) 138422, DOI:10.1016/j.cej.2022.138422.

[10] Jiacheng Li#, Ting Liu#, Yuanli Song#, Mingyu Wang, Liping Liu, Hongwen Zhu, Qi Li, Jin Lin, Hualiang Jiang, Kaixian Chen, Kehao Zhao, Mingliang Wang, Hu Zhou*, Hua Lin*, and Cheng Luo*,Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer, Journal of Medicinal Chemistry  2022, 65, 11034-11057. DOI: 10.1021/acs.jmedchem.2c00257.

[11] Taian Li#, Mong-Feng Chiou#, Yajun Li, Changqing Ye, Min Su, Mengyu Xue, Xiaobin Yuan, Chuanchuan Wang, Wen-Ming Wan, Daliang Li*, and Hongli Bao*, Synthesis of unsymmetrically tetrasubstituted pyrroles and studies of AIEE in pyrrolo[1,2- a ] pyrimidine derivatives, Chemical Sciences, 2022, 13, 5667 – 5673. DOI: 10.1039/d2sc00837h. 

2021年：

[1] Junzhong Lai, Yajuan Fu, Shuoran Tian, Shanlu Huang, Xuan Luo, Lili Lin, Xing Zhang, Hanze Wang, Zhang Lin, Heng Zhao, Shujin Lin, Junhong Zhao, Shan Xu, Daliang Li, Shaoli Cai, Luna Dong, Jing Qian, Jiadi Liang, Qiumei Li, Yong Zhang, Jiqiang Fan, Robert Balderas, Qi Chen. Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice. Molecular therapy. 2021 Feb 9; S1525-0016(21)00072-1.  doi: 10.1016/j.ymthe.2021.02.005. Online ahead of print. 

[2] Lixia Liu, Yingyong Zhang, Tao Liu，Chongrong Ke, Jianzhong Huang, Yajuan Fu, Zhang Lin, Fengjuan Chen, Xiuqin Wu, Qi Chen*. Pyrroloquinoline Quinone Protects against Exercise-induced Fatigue and Oxidative Damage via Improving Mitochondrial Function in Mice. FASEB J. January 2021. https://10.1096/fj.202001977RR. 

[3] Shuoran Tian, Junzhong Lai, Tingting Yu, Qiumei Li and Qi Chen*.   Regulation of Gene Expression Associated With the N6-Methyladenosine (m6A) Enzyme System and Its Significance in Cancer. Front. Oncol., 21 January 2021. https://doi.org/10.3389/fonc.2020.623634.

2020年：

[1] Yajuan Fu, Liqun Zheng, Zhang Lin, Jiaoxia Zeng, Suxing Chen, Junhong Zhao, Yijun Fang, Hao Hu, Hanze Wang, Wei Bao, Qi Chen*, Lijun Sun*. Inhibition of cGAS-mediated interferon response facilitates transgene expression. iSCIENCE, doi: https://doi.org/10.1016/j.isci.2020.101026, 2020. 

[2] Zhihua Feng, Jianghua Chen, Wangwang Liang, Wenzhi Chen, Zhaolong Li, Qi Chen & Shaoli Cai The recombinant pseudorabies virus expressing African swine fever virus CD2v protein is safe and effective in mice. Virol J 17, 180 (2020). https://doi.org/10.1186/s12985-020-01450-7.

[3] Lin J, Li Z, Feng Z, Fang Z, Chen J, Chen W, Liang W, Chen Q. Pseudorabies virus (PRV) strain with defects in gE, gC, and TK genes protects piglets against an emerging PRV variant. J Vet Med Sci. 2020 Jun 30;82(6):846-855. doi: 10.1292/jvms.20-0176. Epub 2020 Apr 24. 

[4] Yixuan Liu, Nanyang Xiao, Hekang Du, Meng Kou, Min Huang, Lili Lin, Shan Xu, Daliang Li &, and Qi Chen*. Celastrol Ameliorates Autoimmune Disorders in Trex1-deficient Mice. Biochemical Pharmacology. 10.1016/j.bcp.2020.114090. 2020.  

[5] Kai Wang, Kun Man, Jiafeng Liu, Yang Liu, Qi Chen, Yong Zhou, Yong Yang. Microphysiological Systems: Design, Fabrication and Applications. ACS Biomaterials Science & Engi. 

[6] Lai J, Luo X, Tian S, Zhang X, Huang S, Wang H, Li Q, Cai S and Chen Q*. Compound C Reducing Interferon Expression by Inhibiting cGAMP Accumulation. Front. Pharmacol. 11:88. doi: 10.3389/fphar.2020.00088. Feb. 28, 2020.2. 

[7] Linye Wu, Langjun Chen, Meng Kou, Yanqiu Dong, Weili Deng, Liang Ge, Hongli Bao, Qi Chen*, Daliang Li*. The ratiometric fluorescent probes for monitoring the reactive inorganic sulfur species (RISS) signal in the living cell. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. https://doi.org/10.1016/j.saa.2020.118141. Feb. 7, 20201.

2019年：

[1] Yuanji Xu, Jiling Wang, Shaoli Cai, Guanghao Chen, Nanyang Xiao, Yajuan Fu,Qi Chen, Sufang Qiu. PNCK depletion inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells in vitro and in vivo. J Cancer 2019; 10(27):6925-6932. doi:10.7150/jca.33698.

[2] Su, Jingqian; Guo, Kai; Huang, Min; Liu, Yixuan; Zhang, Jie; Sun, Lijun; Li, Daliang; Pang, Ka-Lai; Wang, Guangce; Chen, Long; Chen, Youqiang*; Chen Qi*, and Huang, Luqiang*. Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis. August 2019, Frontiers in Pharmacology10. DOI: 10.3389/fphar.2019.00906.  

[3] Gan N, Zhen X, Liu Y, et al. Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase[J]. Nature.2019, 572(7769): 387-391. 

[4] Nanyang Xiao, Jingjing Wei, Shan Xu, Hekang Du, Miaohui Huang, Sitong Zhang, Lijun Sun*, Qi Chen*.cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model. J of Autoimmunity. https://doi.org/10.1016/j.jaut.2019.03.001.

[5] Qianping Luo, Koteswara Rao Bandib, Yanqiu Dong, Hongli Bao, Daliang Li*, Qi Chen*. Synthesis and living cell imaging of a novel fluorescent sensor for selective cupric detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. https://doi.org/10.1016/j.saa.2019.02.013. 2019.

2018年：

[1] Bo Zhang, Weiwei Ye, Yangmiao Ye, Huan Zhou, Abdullah F. U. H. Saeed, Jing Chen, Jinying Lin, Vanja Perčulija, Qi Chen, Chun-Jung Chen, Ming-Xian Chang, Muhammad Iqbal Choudhary & Songying Ouyang. Structural insights into Cas13b-guided CRISPR RNA maturation and recognition. Cell Research 2018

[2] Xiangkai Zhen, Huan Zhou, Wei Ding, Biao Zhou, Xiaolong Xu, Vanja Perčulija, Chun-Jung Chen, Ming-Xian Chang, Muhammad Iqbal Choudhary, Songying Ouyang, Structural basis of AimP signaling molecule recognition by AimR in Spbeta group of bacteriophages. Protein & Cell 2018

[3] Lu Qu, Yan Jiang, Chongyun Cheng, Dong Wu, Bing Meng, Zhenrong Chen, Yanping Zhu, Neil Shaw, Songying Ouyang, Zhi-Jie Liu. Crystal Structure of ATP-Bound Human ABCF1 Demonstrates a Unique Conformation of ABC Proteins. Structure 2018, DOI: https://doi.org/10.1016/j.str.2018.05.019

[4] Haitao Niu, Feng Li, Qingshui Wang, Zhoujie Ye, Qi chen and Yao Lin, High expression level of MMP9 is associated with poor prognosis in patients with clear cell renal carcinoma. PeerJ 6:e5050

[5] Qianping Luo, Yong Fan, Lili Lin, Jingjing Wei, Zuanfang Li, Yongkun Li, Susumu Nakae, Wei Lin and Qi Chen*, Interleukin-33 Protects Ischemic Brain Injury by Regulating Specific Microglial Activities. Neuroscience 385(2018) 75-89

[6] Mengyun Zhang,Yong Dong,Fangxiao Hu,Dan Yang,Qianhao Zhao,Cui Lv,Ying Wang,Chengxiang Xia,Qitong Weng,Xiaofei Liu,Chen Li,Peiqing Zhou,Tongjie Wang,Yuxian Guan,Rongqun Guo,Lijuan Liu,Yang Geng,Hongling Wu,Juan Du,Zheng Hu,Sheng Xu,Jiekai Chen,Aibin He,Bing Liu,Demin Wang,Yong-Guang Yang & Jinyong Wang. Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes. Zhang M, et al. Nat Immunol. 2018. Mar;19(3):279-290

2017年：

[1] Yong Fan,  Qianping Luo,  Jingjing Wei,Ruhui Lin,  Lili Lin, Yongkun Li, Zhaorong Chen, Wei Lin ,  Qi Chen*, Mechanism of Salvianolic Acid B Neuroprotection against Ischemia/Reperfusion Induced Cerebral Injury. Brain Research 2017 . ISSN: 0006-8993  IF: 2.75

[2] Junzhong Lai, Hanze Wang, Qianping Luo, Shanlu Huang, Shujin Lin, Yansong Zheng, and Qi Chen*.The relationship between DNA methylation and Reprimo gene expression in gastric cancer cells. Oncotarget 2017, doi.org/10.18632/oncotarget.21296. ISSN: 1949-2553  IF:5.168

[3]Mei Yu, Yuhong Chen, Hu Zeng , Yongwei Zheng, Guoping Fu, Wen Zhu, Ulrich Broeckel,Praful Aggarwal, Amy Turner, Geoffrey Neale , Cliff Guy, Nan Zhu, Hongbo Chi, Renren Wen & Demin Wang.PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development. Nature Communications 2017,11  DOI: 10.1038/s41467-017-01388-5. ISSN:2041-1723  IF:12.124

[4] Lixia Liu, Xiuqin Wu, Bingchen Zhang, Wei Yang, Yujiao Yin, Qi Chen*. Protective Effects of Tea Polyphenols on Exhaustive Exercise-Induced Fatigue, Inflammation and Tissue Damage. Food Nutr Res 2017. ISSN: 1654-6628  IF: 2.039

[5] Hanze Wang, Huican Ke, Junzhong Lai, Yansong Zheng, Qianping Luo, Qi Chen*. A Modified Bisulfite Conversion Method for the Detection of DNA Methylation. Epigenetics 2017. ISSN: 1559-2294  IF: 4.394

[6] Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, and Zhijian J. Chen. cGAS is Essential for Cellular Senescence. Proc Nat Acad Sci USA 2017.  ISSN: 0027-8424  IF: 9.661

[7] Jingqian Su, Huiying Liu, Kai Guo, Long Chen, Minhe Yang and Qi Chen*. Research Advances and Detection Methodologies for Microbe-Derived Acetylcholinesterase Inhibitors: A Systemic Review. Molecules 2017 22, 176; doi:10.3390/molecules22010176. ISSN: 1420-3049  IF: 2.861

2016年：

[1] Qi Chen, Lijun Sun, Zhijian J Chen*. Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing. Nature Immunology 2016,17(10): 1142-1149.

[2] Hanze Wang, Yansong Zheng, Junzhong Lai, Qianping Luo, Huican Ke, and Qi Chen*. Methylation-Sensitive Melt Curve Analysis of the Reprimo Gene Methylation in Gastric Cancer. PLOS ONE 2016;11(12):e0168635. doi: 10.1371/journal.pone.0168635.

[3] Wujun Jian, Bo Qian, Hongli Bao*, Daliang Li*, AlCl3 catalyzed oxa-Diels-Alder reaction of aromatic aldehydes with simple dienes. Tetrahedron 2016, ISSN:0040-4020  IF: 2.651.  https://doi.org/10.1016/j.tet.2016.10.049

[4] Yan Xu, Yan Chen, Daliang Li, Qing Liu, Zhenyu Xu, Wen-hong Li, TargetLink, a new method for identifying the endogenous target set of a specific microRNA in intact living cells. RNA Biology. DOI:10.1080/15476286.2016.1270006

[5] 肖楠阳、陈骐、蔡少丽*。Epstein-Barr病毒的免疫调控与逃逸机制。微生物学报。2016,56(1):19-25.

      [6] 赵东岳*，林莉莉，温福利。结核分枝杆菌Rv3194c蛋白的表达、纯化及活性鉴定。微生物学报 2016,56(12): 1847-1855.

2015年之前：

[1] Shao M，Liu C，Song Y，Ye W，He W，Yuan G，Gu S，Lin C，Ma L，Zhang Y，Tian W，Hu T，Chen Y. FGF8 signaling sustains progenitor status and multipotency of cranial neural crest-derived mesenchymal cells in vivo and in vitro. J Mol Cell Biol 7:441-454, 2015. doi: 10.1093/jmcb/mjv052.

[2] Ye W, Wang J, Song Y, Sun C, Liu C, Liu H, Zhang Y, Harvey RP, WF, Martin JF, Chen Y. A common Shox2-Nkx2-5 antagonistic mechanism regulates cell fate decision in the pulmonary vein myocardium and sinoatrial node. Development 142: 2521-2532, 2015. doi: 10.1242/dev.120220.

[3] J Su，M Yang.Huperzine A production by Paecilomyces tenuis YS-13, an endophytic fungus isolated from Huperzia serrata.Natural Product Research Formerly Natural Product Letters 2015, 29(11):1-7.

[4] Huang Z, Hu X, Lin C, Li H, Huang Y, Chen Y, Zhang Y. Genome-Wide Analysis of Gene Expression in the Cap Stage of the Human Embryonic Tooth Germ. J Mol His 45: 609-617, 2014. doi: 10.1007/s10735-014-9580-5). 

[5] Liu H, Chen C, Ye W, Espinoza-Lewis R, Hu X, Zhang Y, Chen Y. Phophorylation of Shox2 isrequired for its function to control sinoatrial node formation. JAHA 3:e000796, 2014.

[6] He F, Hu X, Xiong W, Li L, Lind L, Shen B, Yang L, Gu S, Zhang Y, Chen Y. Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect. Dev BioI 391: 170 -181，2014. 

[7] Hu X, Lin C, Shen B, Ruan N, Guan Z, Chen Y, Zhang Y. Conserved odontogenic potentialinembryonicdentaltissue. J Dental Res 93: 490-495, 2014 . 

[8] Zhang Y, Chen Y. Bioengineering of a Whole tooth: Progress and Challenge. BMC Cell Regeneration 3:8, 2014. doi: 10.1186/2045-9769-3-8. 

[9] Liu C, Gu S, Sun C, Ye W, Song Z, Zhang Y, Chen Y. FGF signaling sustains odontogenicfate of dental mesenchyme by suppressing-catenin signaling. Development 140: 4375-4385, 2013. 

[10] Hu X, Xu S, Lin C, Zhang L, Chen Y, Zhang Y. Precise chronology of differentiation of developing human primary dentition . Histochem Cell Biol141 :221-227, 2014.

[11] Hu X, Zhang S, Chen G, Lin C, Chen Y, Zhang Y. Expression of signaling molecules in the developing human Primary dentition. BMC Dev Biol 13:11 2013  

[12] 沈阳坤、郑志泉、蔡少丽*。CRISPR/Cas9系统在疾病模型和基因治疗中的应用。中国生物化学与分子生物学学报 2015,31(8):786-794.

[13] 赵东岳、陈金锋、陈骐*。阿尔茨海默病（AD）与炎性调控。中国生物化学与分子生物学学报 2015 (7): 689-693.

[14] 许姗、赖俊忠、陈骐*。肿瘤干细胞表面标志物及主要信号通路。中国生物化学与分子生物学学报 2015 (10):1017-1024.